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1.18307

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Octane-1-sulfonic acid sodium salt

for ion pair chromatography LiChropur

Synonym(s):

Octane-1-sulfonic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C8H17NaO3S
CAS Number:
Molecular Weight:
216.27
MDL number:
UNSPSC Code:
12352107
EC Index Number:
226-195-4
NACRES:
NB.21
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Quality Level

Assay

≥99% (acidimetric)

form

solid

technique(s)

ion pair chromatography: suitable

loss

≤2 loss on drying, 120°C; 4h; vacuum

transmittance

200 nm, ≥70%
220 nm, ≥90%
250 nm, ≥98%
(0.005 M; 1 cm in H2O)

pH

5.5-7.5 (20 °C, 100 g/L in H2O)

mp

>300 °C

bulk density

345 kg/m3

suitability

passes test for identity (IR)

storage temp.

15-25°C

SMILES string

[Na+].[S](=O)(=O)([O-])CCCCCCCC

InChI

1S/C8H18O3S.Na/c1-2-3-4-5-6-7-8-12(9,10)11;/h2-8H2,1H3,(H,9,10,11);/q;+1/p-1

InChI key

HRQDCDQDOPSGBR-UHFFFAOYSA-M

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General description

Octane-1-sulfonic acid sodium salt is a commonly used ion-pair reagent in ion-pair chromatography. ​Adding octane-1-sulfonic acid sodium salt to the mobile phase in chromatography can help enhance chromatographic separation by modifying the polarity gap between analytes.[1][2]

Application

Octane-1-sulfonicacid sodium salt can be used as a mobile phase component in Reverse-PhaseHigh-Performance Liquid Chromatography (RP-HPLC) to facilitate the separation and quantification of amisulpride in the pharmaceutical tablet formulation.[3]

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Analytical method development and its validation for estimation of amisulpride by reversed phase high performance liquid chromatography (RP-HPLC)
Gupta P, et al.
International Journal of Research in Pharmaceutical Sciences, 4, 542-549 (2013)
The effect of chromatographic conditions on the separation of selected alkaloids in RP-HPTLC
Petruczynik A, et al.
Journal of Chromatographic Science, 43(4), 183-194 (2005)
Development and validation of an ion-pair HPLC chromatography for simultaneous determination of lactone and carboxylate forms of SN-38 in nanoparticles
Ebrahimnejad P, et al.
Journal of food and drug analysis, 17(4), 8-8 (2009)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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