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840052C

Avanti

Heart PC

Avanti Research™ - A Croda Brand 840052C

Synonym(s):

L-α-phosphatidylcholine (Heart, Bovine)

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About This Item

CAS Number:
17708-90-6
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840052C-25mg)
pkg of 2 × 4 mL (840052C-200mg)
pkg of 5 × 4 mL (840052C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840052C

concentration

10 mg/mL (840052C-25mg)
25 mg/mL (840052C-200mg)
25 mg/mL (840052C-500mg)

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

General description

Contains ~40% plasmalogen ether lipid
Phosphatidylcholine (PC) is a phospholipid, that comprises 40-50% of the total phospholipid content in the cell membrane. It is an abundant phospholipid in all mammalian cells and cellular organelles. PC is a glycerophospholipid. It is synthesized by the Kennedy pathway.

Application

Heart PC has been used in the Mycobacterium lipid extraction and in β- Hexosaminidase release and calcium mobilization assays.

Biochem/physiol Actions

Phosphatidylcholine (PC) in the liver is responsible for the production of very low density lipoproteins (VLDL).

Packaging

5 mL Clear Glass Sealed Ampule (840052C-200mg)
5 mL Clear Glass Sealed Ampule (840052C-25mg)
5 mL Clear Glass Sealed Ampule (840052C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(9 Pt B), 1558-1558 (2017)
Marianne S Jurkowitz et al.
Biochimica et biophysica acta, 1848(2), 742-751 (2014-12-03)
Lysoplasmalogenase catalyzes hydrolytic cleavage of the vinyl-ether bond of lysoplasmalogen to yield fatty aldehyde and glycerophospho-ethanolamine or glycerophospho-choline. We recently purified lysoplasmalogenase from rat liver microsomes and identified the protein as TMEM86B, an integral membrane protein that is a member
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific Reports, 5(9 Pt B), 16787-16787 (2015)
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
Torres-Atencio I, et al.
American Journal of Respiratory and Critical Care Medicine, 198(6), 813-816 (2018)
Ivan U Kouzel et al.
Journal of lipid research, 54(3), 692-710 (2012-12-19)
Glycosphingolipids (GSLs) of the globo-series constitute specific receptors for Shiga toxins (Stxs) released by certain types of pathogenic Escherichia coli strains. Stx-loaded leukocytes may act as transporter cells in the blood and transfer the toxin to endothelial target cells. Therefore

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