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Key Documents

810335C

Avanti

18:1 Cy5 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(Cyanine 5)

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About This Item

Empirical Formula (Hill Notation):
C73H118ClN4O9P
CAS Number:
2260669-61-0
Molecular Weight:
1262.17
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810335C-1mg)
pkg of 5 × 1 mL (810335C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (810335C-1mg)
1 mg/mL (810335C-5mg)

shipped in

dry ice

storage temp.

−20°C

Application

18:1 Cy5 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(Cyanine 5), chloroform has been used:
  • as a standard for the estimation of absolute density of Cy5 labeled Trx-His6-NCav-CT on supported lipid bilayers (SLB)
  • in annexin-coated vesicle production
  • to label vesicle types in order to optically distinguish them from other vesicles and to initiate biochemical reactions in a cell-mimetic compartment

Biochem/physiol Actions

Fluorescent labelled lipids are generally useful in cell biology and biophysical studies. Cellular events involving lipids such as lipid domain generation, disaggregation and re-organization can be studied with fluorescent lipids. They are also useful in analyzing the physical properties of lipid bilayers.

Packaging

5 mL Amber Glass Screw Cap Vial (810335C-1mg)
5 mL Amber Glass Screw Cap Vial (810335C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiandeng Wu et al.
Molecular cell, 73(5), 971-984 (2019-01-22)
Both the timing and kinetics of neurotransmitter release depend on the positioning of clustered Ca2+ channels in active zones to docked synaptic vesicles on presynaptic plasma membranes. However, how active zones form is not known. Here, we show that RIM
Guido Bolognesi et al.
Nature communications, 9(1), 1882-1882 (2018-05-16)
Constructing higher-order vesicle assemblies has discipline-spanning potential from responsive soft-matter materials to artificial cell networks in synthetic biology. This potential is ultimately derived from the ability to compartmentalise and order chemical species in space. To unlock such applications, spatial organisation
Jamie B Strachan et al.
Journal of colloid and interface science, 576, 241-251 (2020-05-20)
Cubosomes form part of the next generation of lipid nanoparticle drug delivery vehicles, enabling higher drug encapsulation efficiency, particularly for lipophilic drugs, compared to traditional liposome formulations. However, the mechanism of interaction of cubosome lipid nanoparticles with cells and their
Margrethe A Boyd et al.
Biophysical journal, 115(7), 1307-1315 (2018-09-17)
Cells dynamically regulate their membrane surface area during a variety of processes critical to their survival. Recent studies with model membranes have pointed to a general mechanism for surface area regulation under tension in which cell membranes unfold or take
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
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