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Sigma-Aldrich® TLC Plates

silica gel 60 matrix

Synonym(s):

Sigma-Aldrich thin-layer chromatography plates

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About This Item

UNSPSC Code:
41115711
eCl@ss:
32110504
NACRES:
NC.07

material

polyester support
silica gel 60 matrix

Quality Level

100

feature

binder Organic Polymer
fluorescent indicator

packaging

pkg of 25 plates

manufacturer/tradename

Sigma-Aldrich

technique(s)

thin layer chromatography (TLC): suitable

L × W

20 cm × 20 cm

layer thickness

200 μm

particle size

5-17 μm

pore size

60 Å medium pore diameter

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General description

Thin-layer chromatography (TLC) plates for adsorption, partition, and ion-exchange techniques. Six media choices with glass, polyester, and aluminum backings. Silica-based adsorbent layers in Sigma-Aldrich TLC plates incorporate a polymeric binder; highly purified silica gel plates incorporate a gypsum/polymer binder.
  • Silica gel - for weakly to strongly polar separations, pore size 60 Å
  • High purity silica gel - acid washed for separation of aflatoxins
  • Cellulose - for partition chromatography, (SigmaCell Type 100 Cellulose)
  • Cellulose PEI - for separation of weak anions (amino acids, peptides) PEI plates may turn slightly yellow, affecting separation. Pre-develop plates in distilled water to minimize yellow color.
  • Chiral silica - for separation of optically active isomers by ligand exchange, pore size 60Å

Application

Sigma-Aldrich TLC Plates was used for TLC analysis during GTPase activity assay and lipid extraction/analysis.

Legal Information

SIGMA-ALDRICH is a registered trademark of Merck KGaA, Darmstadt, Germany

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Chuang-Rung Chang et al.
The Journal of biological chemistry, 282(30), 21583-21587 (2007-06-08)
Mitochondria in cells comprise a tubulovesicular reticulum shaped by dynamic fission and fusion events. The multimeric dynamin-like GTPase Drp1 is a critical protein mediating mitochondrial division. It harbors multiple motifs including GTP-binding, middle, and GTPase effector (GED) domains that are
Heiko Runz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(5), 1679-1689 (2002-03-07)
Generation of amyloid-beta (Abeta) from the amyloid precursor protein (APP) requires proteolytic cleavage by two proteases, beta- and gamma-secretase. Several lines of evidence suggest a role for cholesterol on secretase activities, although the responsible cellular mechanisms remain unclear. Here we
Sofi Eriksson et al.
Nature communications, 6, 6479-6479 (2015-03-21)
Across phyla, reduced nicotinamide adenine dinucleotide phosphate (NADPH) transfers intracellular reducing power to thioredoxin reductase-1 (TrxR1) and glutathione reductase (GR), thereby supporting fundamental housekeeping and antioxidant pathways. Here we show that a third, NADPH-independent pathway can bypass the need for

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