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Key Documents

QBD11100

Sigma-Aldrich

Biotin-dPEG®3-oxyamine HCl

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C18H35ClN4O6S
Molecular Weight:
471.01
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reagent type: cross-linking reagent

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCO[NH3+].[Cl-]

Features and Benefits

Biotin-dPEG®3-oxyamine.HCl allows biotin labeling of molecules with free aldehydes or ketones. Biotin-dPEG®3-oxyamine-containing products forms oximes. These reagents are highly useful for labeling carbohydrates, glycoproteins, and other molecules with biotin following oxidation of the carbohydrate or glycan with sodium periodate or by chemical installation of an aldehyde or ketone on the target molecule. The dPEG® spacer is a single molecular weight PEG (16.6 Å) that provides excellent water solubility while extending the biotin moiety away from the surface of the labeled molecule for enhanced binding to avidin or streptavidin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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