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QBD10318

Sigma-Aldrich

m-dPEG®24-amine

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C49H101NO24
Molecular Weight:
1088.32
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carboxyl reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

Features and Benefits

The m-dPEG®24-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). This single molecular weight methoxy-terminated dPEG® molecule is hydrophilic and non-immunogenic with a spacer of exact length (86.1 Å). Modification with m-dPEG® reagent can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®24-amine products react with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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