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P22370

Sigma-Aldrich

trans-2-Phenylcyclopropylamine hydrochloride

97%

Synonym(s):

Tranylcypromine

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About This Item

Linear Formula:
C6H5C3H4NH2·HCl
CAS Number:
1986-47-6
Molecular Weight:
169.65
MDL number:
MFCD00063602
UNSPSC Code:
12352100
PubChem Substance ID:
24898296
NACRES:
NA.22

Assay

97%

form

solid

optical activity

[α]/D −1 to +1.0°, c = 1 in H2O

mp

162-169 °C (lit.)

storage temp.

2-8°C

SMILES string

Cl.N[C@@H]1C[C@H]1c2ccccc2

InChI

1S/C9H11N.ClH/c10-9-6-8(9)7-4-2-1-3-5-7;/h1-5,8-9H,6,10H2;1H/t8-,9+;/m0./s1

InChI key

ZPEFMSTTZXJOTM-OULXEKPRSA-N

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Related Categories

Biochem/physiol Actions

Non-selective MAO-A/B inhibitor.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000218050
0000196521
BGBC2936V
BGBC2935V
BGBC2546V

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Kaisa A Salminen et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(12), 1891-1904 (2015-09-25)
The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including compounds of natural origin, which could inhibit CYP2C19, potentially causing clinically relevant metabolism-based drug
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European journal of pediatrics, 174(4), 509-518 (2014-09-25)
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James M Hill et al.
Science translational medicine, 6(265), 265ra169-265ra169 (2014-12-05)
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Chemico-biological interactions, 230, 9-20 (2015-02-07)
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