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Key Documents

O3303

Sigma-Aldrich

1,8-Octanediol

98%

Synonym(s):

Octamethylene glycol

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About This Item

Linear Formula:
HO(CH2)8OH
CAS Number:
Molecular Weight:
146.23
Beilstein:
1633499
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

bp

172 °C/20 mmHg (lit.)

mp

57-61 °C (lit.)

SMILES string

OCCCCCCCCO

InChI

1S/C8H18O2/c9-7-5-3-1-2-4-6-8-10/h9-10H,1-8H2

InChI key

OEIJHBUUFURJLI-UHFFFAOYSA-N

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Application

1,8-Octanediol can undergo:
  • Polycondensation with citric acid to form biodegradable poly(1,8-octanediol citrate)(POC) crosslinked bioelastomer which can be blended with various additives.
  • Fischer esterification with dicarboxylic acids to form diol-based macromers.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

248.0 °F - closed cup

Flash Point(C)

120 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis and Characterization of Diol-Based Unsaturated Polyesters: Poly (diol fumarate) and Poly (diol fumarate-co-succinate).
Tatara AM, et al.
Biomacromolecules, 18(6), 1724-1735 (2017)
Chitin nanocrystal enhanced wet adhesion performance of mussel-inspired citrate-based soft-tissue adhesive.
Xu Y, et al.
Carbohydrate Polymers, 190, 324-330 (2018)
Kai-Hee Huong et al.
International journal of biological macromolecules, 116, 217-223 (2018-05-04)
Long carbon chain alkanediols are used in the production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)], however these substrates possess high toxicity towards bacterial cells. This study demonstrated the effective utilisation of a long carbon chain alkanediol, namely 1,8-octanediol, to enhance the yield and
Yun He et al.
Acta biomaterialia, 93, 180-191 (2019-03-31)
The design and development of bioactive materials that are inherently conducive for osteointegration and bone regeneration with tunable mechanical properties and degradation remains a challenge. Herein, we report the development of a new class of citrate-based materials with glycerophosphate salts
Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications.
Zeimaran E, et al.
Carbohydrate Polymers, 175, 618-627 (2017)

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