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Key Documents

M9894

Sigma-Aldrich

4-Methoxy-2-naphthylamine

≥98%

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About This Item

Empirical Formula (Hill Notation):
C11H11NO
CAS Number:
Molecular Weight:
173.21
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

solid

storage temp.

−20°C

SMILES string

COc1cc(N)cc2ccccc12

InChI

1S/C11H11NO/c1-13-11-7-9(12)6-8-4-2-3-5-10(8)11/h2-7H,12H2,1H3

InChI key

SFKZPTYRENGBTJ-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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B Ulbricht et al.
Biological chemistry Hoppe-Seyler, 376(7), 407-414 (1995-07-01)
The cysteine proteases cathepsin B and cathepsin L are very likely involved in invasive processes of normal and malignant cells, they become relevant for a number of diseases and are possibly prognostic markers for the outcome of human lung cancer.
C N Kennett et al.
Journal of periodontal research, 29(3), 203-213 (1994-05-01)
Cathepsin B activity was demonstrated histochemically in unfixed cryostat sections of inflamed human gingiva using the 2-methoxy-4-naphthylamide (MNA) substrates Z-Val-Lys-Lys-Arg-MNA and Z-Ala-Arg-Arg-MNA with a post-azo-coupling technique. Enzyme localisation was confirmed by immunocytochemistry with polyclonal sheep anti-human cathepsin B. In both
Heidi A Kluess et al.
Medicine, 98(13), e14982-e14982 (2019-03-29)
The purpose was to investigate changes in neuropeptide Y (NPY) protein and dipeptidyl peptidase IV (DPP-IV) activity in the plasma and saliva in normally cycling women and women after menopause. We recruited 7 cycling women and 7 postmenopausal women for
S H Randell et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 33(7), 677-686 (1985-07-01)
Dipeptidyl peptidase II (DPP II) in normal rat lung was evaluated by the enzymes' ability to hydrolyze Lys-Ala or Lys-Pro derivatives of 4-methoxy-2-naphthylamine (MNA). For visualization of this activity, the liberated MNA was coupled with fast blue B for light
I Steinsträsser et al.
Journal of pharmaceutical sciences, 86(3), 378-383 (1997-03-01)
Metabolism studies on organized HaCaT keratinocyte cell sheets are reported. Cells were grown on porous membranes to form organized cell sheets of several cell layers, which were considered as a model of viable epidermis. Metabolism was studied by reflection kinetics

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