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G307

Sigma-Aldrich

Galvinoxyl, free radical

Synonym(s):

2,6-Di-tert-butyl-α-(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadien-1-ylidene)-p-tolyloxy, free radical

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About This Item

Empirical Formula (Hill Notation):
C29H41O2
CAS Number:
Molecular Weight:
421.63
EC Number:
MDL number:
UNSPSC Code:
12352000
PubChem Substance ID:
NACRES:
NA.22

mp

158-159 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)(C)c1cc(\C=C2\C=C(C(=O)C(=C2)C(C)(C)C)C(C)(C)C)cc(c1[O])C(C)(C)C

InChI

1S/C29H41O2/c1-26(2,3)20-14-18(15-21(24(20)30)27(4,5)6)13-19-16-22(28(7,8)9)25(31)23(17-19)29(10,11)12/h13-17H,1-12H3

InChI key

GNZDAXRYGVFYPU-UHFFFAOYSA-N

Application

Free radical and free-radical scavenger.

Storage Class Code

11 - Combustible Solids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Lan-Fen Wang et al.
Bioorganic chemistry, 33(2), 108-115 (2005-03-25)
To improve the radical-scavenging activity of catechin, a planar catechin analogue was designed and synthesized by Fukuhara [J. Am. Chem. Soc. 124 (2002) 5952]. Although the planar catechin is less active than quercetin, it is much more active than catechin
Shuichi Shimakawa et al.
Lipids, 38(3), 225-231 (2003-06-06)
Nitroxyl radicals are known to act as radical scavenging antioxidants. In the present study, a lipophilic nitroxyl radical, cyclohexane-1-spiro-2'-(4'-oxyimidazolidine-1'-oxyl)-5'-spiro-1"-cyclohexane (nitroxyl radical I) was synthesized and its antioxidant capacity was assessed in comparison with a hydrophilic nitroxyl radical, 4-hydroxy-2,2,6,6-tetra-methylpiperidine-N-oxyl (Tempol). Both
Jens Z Pedersen et al.
The Journal of pharmacy and pharmacology, 59(12), 1721-1728 (2007-12-07)
Polyphenolic coumarins are known to act as antioxidants in biological systems, but it is difficult to distinguish their antioxidant activity from the many other effects they produce in cells. We have determined the radical scavenging capacity of 22 structurally related
Abolfazl Barzegar et al.
PloS one, 6(10), e26012-e26012 (2011-10-22)
Curcumin has many pharmaceutical applications, many of which arise from its potent antioxidant properties. The present research examined the antioxidant activities of curcumin in polar solvents by a comparative study using ESR, reduction of ferric iron in aqueous medium and
Mizuki Takashima et al.
BioFactors (Oxford, England), 38(3), 240-248 (2012-04-11)
Thiol compounds exert diverse functions in the defense network against oxidative stress in vivo. Above all, the role of glutathione in the enzymatic removal of hydrogen peroxide and lipid hydroperoxides has been well established. The scavenging of reactive free radicals

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