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Key Documents

934097

Sigma-Aldrich

Ovine collagen

methacrylate functionalized, low endotoxin

Synonym(s):

CollOvine MA

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.28

Quality Level

form

powder

impurities

Bioburden, none detected
≤0.1 EU/mg Endotoxin

color

white to off-white

functional group

methacrylate

storage temp.

2-8°C

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General description

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Methacrylate functionalized collagen is a polymerizable hydrogel material derived from low endotoxin ovine collagen. The addition of photocrosslinkable methacrylate functional groups allows the photopolymerization of biocompatible, biodegradable, and non-immunogenic hydrogels which can encapsulate cells and be used in many biomedical applications. This methacrylate functionalized collagen is also a great alternative to other naturally derived collagens such as those derived from bovine or porcine.

Application

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

Features and Benefits

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

Legal Information

CollOvine is a trademark of OviGenex LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Collagen as Bioink for Bioprinting: A Comprehensive Review
Osidak E O, et al.
International Journal of Bioprinting, 6, 270-270 (2020)
Elizabeth E Antoine et al.
Tissue engineering. Part B, Reviews, 20(6), 683-696 (2014-06-14)
Type I collagen hydrogels have been used successfully as three-dimensional substrates for cell culture and have shown promise as scaffolds for engineered tissues and tumors. A critical step in the development of collagen hydrogels as viable tissue mimics is quantitative
Atiqah Salleh et al.
Biomedicines, 10(4), 816-816 (2022-04-24)
Tissue engineering products have grown rapidly as an alternative solution available for chronic wound and burn treatment. However, some drawbacks include additional procedures and a lack of antibacterial properties that can impair wound healing, which are issues that need to
Jana Stepanovska et al.
Biomedicines, 9(9), 1137-1137 (2021-09-29)
Bioprinting is a modern tool suitable for creating cell scaffolds and tissue or organ carriers from polymers that mimic tissue properties and create a natural environment for cell development. A wide range of polymers, both natural and synthetic, are used

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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