927473
CA-alkyne
≥95%
Synonym(s):
2-Chloro-N-(hex-5-yn-1-yl)acetamide
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About This Item
Empirical Formula (Hill Notation):
C8H12ClNO
CAS Number:
Molecular Weight:
173.64
UNSPSC Code:
12352101
NACRES:
NA.21
Application
CA-alkyne is a probe that can be used for labeling cysteines through alkylation. For the corresponding negative control, see CA-nitrile. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitative applications. The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis. Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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