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924113

Sigma-Aldrich

(R,E)-1-(2-Aminoethyl)cyclooct-4-en-1-ol, 5-ax-Hydroxy-5-eq-(2-aminoethyl)-trans-cyclooctene

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Synonym(s):

Amine-a-TCO

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About This Item

Empirical Formula (Hill Notation):
C10H19NO
Molecular Weight:
169.26

storage temp.

−20°C

Quality Level

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Jessica E Pigga et al.
Angewandte Chemie (International ed. in English), 60(27), 14975-14980 (2021-03-21)
trans-Cyclooctenes (TCOs) are essential partners in the fastest known bioorthogonal reactions, but current synthetic methods are limited by poor diastereoselectivity. Especially hard to access are hydrophilic TCOs with favorable physicochemical properties for live cell or in vivo experiments. Described is a

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