911240

Poly(ethylene glycol) linear dendron

carboxyl terminated, PEG M_n 10,000, generation 4

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₅₉₄H₁₀₉₆O₃₂₁
• Molecular Weight: 13374.87
• UNSPSC Code: 51171641
• NACRES: NA.21

Properties

• form: solid
• mol wt: PEG M_n 10,000; generation 4
• no. Surface Groups: 16
• color: white to off-white
• storage temp.: −20°C

Description

General description

• Polymer architecture: PEG-linear dendron
• Generation: 4
• PEG average Mn: 10,000
• End Group Functionality: Carboxylic acid
• No. Surface Groups: 16
• Calculated Mol. Wt.: 13374.98 g/mol
• Bis-MPA = 2,2-Bis(hydroxymethyl)propionic acid

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrons feature excellent solubility in water and a high degree of functionality per PEG chain, enabling use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable