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Key Documents

900741

Sigma-Aldrich

Gelatin methacryloyl

gel strength 170-195 g Bloom, degree of substitution: 60%

Synonym(s):

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate

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About This Item

Linear Formula:
(C40H59N11O13)n
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

solid

storage temp.

2-8°C

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Application

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering and 3D printing. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin methacrylate has been explored in drug delivery applications in the form of microspheres and hydrogels.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Facile one-step micropatterning using photodegradable methacrylated gelatin hydrogels for improved cardiomyocyte organization and alignment.
Tsang K, et al.
Advances in Functional Materials, 25(6), 977-986 (2015)
Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs.
Boere KWM, et al.
Acta Biomaterialia, 10(6), 2602-2611 (2014)
Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, et al.
Advanced Helathcare Materials (2015)
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV, et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as

Articles

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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Protocols

Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.

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