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850489

Sigma-Aldrich

L-Tyrosine methyl ester hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)COOCH3 · HCl
CAS Number:
3417-91-2
Molecular Weight:
231.68
Beilstein:
3917353
EC Number:
222-313-3
MDL number:
MFCD00012607
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24888297
NACRES:
NA.22

form

powder

Quality Level

200

optical activity

[α]25/D +74.0°, c = 3 in pyridine

reaction suitability

reaction type: solution phase peptide synthesis

mp

192 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl.COC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI

1S/C10H13NO3.ClH/c1-14-10(13)9(11)6-7-2-4-8(12)5-3-7;/h2-5,9,12H,6,11H2,1H3;1H/t9-;/m0./s1

InChI key

VXYFARNRGZWHTJ-FVGYRXGTSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000293122
BGBC0359V
BGBB8603
1433117V
1433117

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Francesca Fontana et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-14)
Configurationally stable 5-aza[6]helicene (1) was envisaged as a promising scaffold for non-conventional ionic liquids (IL)s. It was prepared, purified, and separated into enantiomers by preparative HPLC on a chiral stationary phase. Enantiomerically pure quaternary salts of 1 with appropriate counterions
M Tatsuta et al.
International journal of cancer, 48(5), 785-788 (1991-07-09)
The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 512 mg/kg body weight, every other day after
Separation of 125I-labelled prostaglandin E2-tyrosine methyl ester by reversed-phase high-performance liquid chromatography.
I Mucha et al.
Journal of chromatography, 438(1), 111-116 (1988-04-01)
M J Barjavel et al.
European journal of pharmacology, 258(3), 173-178 (1994-06-13)
The effects of the methyl esters of L-tyrosine (L-Tyr-OMe) and L-tryptophan (L-Trp-OMe) on the analgesic action of trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidin)cyclohexyl]-benzene acetamide methane sulfonate (U-50,488H), a kappa-opioid receptor agonist, were determined in male Swiss-Webster mice using the tail-flick test. Intraperitoneal injections of U-50,488H
T Oishi et al.
Journal of neurochemistry, 42(3), 894-896 (1984-03-01)
Dopamine and norepinephrine concentrations in the stomach, duodenum, and brain were measured after subcutaneous injection of tyrosine methyl ester in the rat. Tyrosine significantly increased dopamine concentrations in each tissue without altering norepinephrine levels. The increase in dopamine concentration in
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