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808709

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, biotin terminated, PEG 5000, OD 50, dispersion in H2O

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About This Item

EC Number:
UNSPSC Code:
12141717
NACRES:
NA.23

material

PEG 5000

Quality Level

form

dispersion in H2O
nanoparticles

composition

, 2.99E+14 particles/mL

packaging

pkg of 0.5 mL

concentration

3.04 mg/mL in H2O

OD

50

surface area

30.8 m2/g

diameter

10 nm

pH

5-7

density

1.00 g/cm3

λmax

515-520 nm

functional group

biotin

storage temp.

2-8°C

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles PEG 5000 biotin terminated.

Application

Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.
Gold nanoparticles 10 nm diameter, biotin terminated, PEG 5000, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.

Legal Information

Product of Cytodiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Localized surface plasmon resonance (LSPR) of polyelectrolyte-functionalized gold-nanoparticles for bio-sensing
Li X, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 332(2-3), 172-179 (2009)
Colorimetric biosensing of pathogenss using gold nanoparticles
Verma MS, et al.
Biotechnology Advances, 33(6), 666-680 (2015)
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 33(6), 666-680 (2020)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)

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