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762016

Sigma-Aldrich

3-Azido-1-propanamine

≥95%

Synonym(s):

3-Azidopropylamine

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About This Item

Empirical Formula (Hill Notation):
C3H8N4
CAS Number:
Molecular Weight:
100.12
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥95%

form

liquid

reaction suitability

reaction type: click chemistry

refractive index

n20/D 1.471

density

1.020 g/mL at 25 °C

storage temp.

−20°C

SMILES string

NCCCN=[N+]=[N-]

InChI

1S/C3H8N4/c4-2-1-3-6-7-5/h1-4H2

InChI key

OYBOVXXFJYJYPC-UHFFFAOYSA-N

General description

3-Azido-1-propanamine can be used to functionalize:
  • Bismethylolpropionic acid (bis-MPA) monomers with azide functional group to generate high-generation dendrimers.,
  • Clickable zinc tetraphenylporphyrin scaffold with an azido group through click chemistry applicable in photodynamic therapy.

Application

Amine modified azide for click chemistry.
3-Azido-1-propanamine may be used in the synthesis of mannopyranoside dendrimers for studying multivalent carbohydrate-protein interactions.

Pictograms

FlameSkull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

140.0 °F

Flash Point(C)

60 °C


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Xiaoqiang Chen et al.
Biomaterials, 122, 130-140 (2017-01-24)
The development of multifunctional reagents for simultaneous specific near-infrared (NIR) imaging and phototherapy of tumors is of great significance. This work describes the design of a cathepsin B-activated fluorescent probe (CyA-P-CyB) and its applications as an NIR imaging probe for
Synthesis of mono-, di-and triporphyrin building blocks by click chemistry for photodynamic therapy application
Gazzali AM, et al.
Tetrahedron, 73(5), 532-541 (2017)
Two-dimensional ultrafast vibrational spectroscopy of azides in ionic liquids reveals solute-specific solvation
Dutta S, et al.
Physical Chemistry Chemical Physics, 17(40), 26575-26579 (2015)
Mariano Ortega-Muñoz et al.
Nanoscale, 11(16), 7850-7856 (2019-04-10)
Activated carbon nanodots functionalized with acid anhydride groups (AA-CNDs) are prepared by one-pot water-free green thermolysis of citric acid. As a proof of concept of their capabilities as appealing and versatile platforms for accessing engineering nanoconstructs, the as-prepared AA-CNDs have
Dual display of proteins on the yeast cell surface simplifies quantification of binding interactions and enzymatic bioconjugation reactions.
Lim S, et al.
Biotechnology Journal, 12(5) (2017)

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