74104

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

≥97.0% (calc. on dry substance, AT), for peptide synthesis

• Synonym(s): DMTMM, MMTM
• Empirical Formula (Hill Notation): C₁₀H₁₇ClN₄O₃
• CAS Number: 3945-69-5
• Molecular Weight: 276.72
• Beilstein: 8026872
• MDL number: MFCD03613550
• UNSPSC Code: 12352005
• PubChem Substance ID: 57652501
• NACRES: NA.22

Properties

• product name: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, 95% (HPLC)
• Assay: 95% (HPLC)
• form: powder
• reaction suitability: reaction type: Coupling Reactions
• impurities: ≤17 wt. % water
• application(s): peptide synthesis
• functional group: ether
• storage temp.: −20°C
• SMILES string: [Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2
• InChI: 1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1
• InChI key: BMTZEAOGFDXDAD-UHFFFAOYSA-M

Description

Application

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride can be used as a condensing agent for the following transformations:

• Condensation of carboxylic acids and amines to the corresponding amides in tetrahydrofuran.
• Esterification of carboxylic acids with alcohols to the corresponding esters.
• Conversion of carboxylic acids to the corresponding Weinreb amides in protic solvents.

Reagent for activating carboxylic acids in solution and solid phase peptide synthesis; superior or comparable to the most popular coupling reagents

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H314
• Precautionary Statements: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 198.5 °F - closed cup
• Flash Point(C): 92.5 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves