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Sigma-Aldrich

PAMAM Dendrimer Kit, generations 0-3

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About This Item

UNSPSC Code:
12162002
eCl@ss:
32161000
NACRES:
NA.23

description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

storage temp.

2-8°C

General description

PAMAM Dendrimer Kit, generations 0-3 consists of a class of hyper-branched polymers with an ethylene diamine core, and amido amine as a branching structure that facilitates the formation of amine terminated full generation or carboxyl-terminated half generation dendrimers. It can be used in the functionalization of polymer with drugs, nucleic acids and imaging systems.

Packaging

unit weight includes solvent

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Kit Components Also Available Separately

Product No.
Description
SDS
  • 412368PAMAM dendrimer, ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol 1 gSDS
  • 412384PAMAM dendrimer, ethylenediamine core, generation 1.0 solution, 20 wt. % in methanol 1 gSDS
  • 412406PAMAM dendrimer, ethylenediamine core, generation 2.0 solution, 20 wt. % in methanol 1 gSDS
  • 412422PAMAM dendrimer, ethylenediamine core, generation 3.0 solution, 20 wt. % in methanol 1 gSDS

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3

Target Organs

Eyes,Central nervous system, Respiratory system

Storage Class Code

3 - Flammable liquids

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

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Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
Sadekar S and Ghandehari H
Advanced Drug Delivery Reviews, 64(6), 571-588 (2012)
Anti-angiogenesis effect of generation 4 polyamidoamine/vascular endothelial growth factor antisense oligodeoxynucleotide on breast cancer in vitro
Gu S, et al.
Journal of Zhejiang University. Science, 10(3), 159-167 (2009)
Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: an in vitro study
Cheng Y, et al.
European Journal of Medicinal Chemistry, 42(7), 1032-1038 (2007)
Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: a potential oral delivery system?
Wiwattanapatapee R, et al.
Pharmaceutical Research, 17(8), 991-998 (2000)

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Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

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