438227
Hydroxylamine solution
50 wt. % in H2O
Synonym(s):
HDA
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About This Item
Linear Formula:
NH2OH
CAS Number:
Molecular Weight:
33.03
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
vapor pressure
9 mmHg ( 40 °C)
Quality Level
form
liquid
concentration
50 wt. % in H2O
bp
>100 °C
density
1.078 g/mL at 25 °C
SMILES string
NO
InChI
1S/H3NO/c1-2/h2H,1H2
InChI key
AVXURJPOCDRRFD-UHFFFAOYSA-N
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General description
Hydroxylamine is a weak base that is mainly used as a reducing agent in organic reactions.
Application
Reactant for preparation of:
- Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)
- Hydroxyaminoguanidines as anti-cancer agents
- Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation
- Carboxamide derivatives of ofloxacin with improved antimicrobial properties
- Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors
- HIV integrase inhibitors
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
Target Organs
Blood, Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Ian R Kelsall et al.
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Assembly of cyclic peptide dendrimers from unprotected linear building blocks in aqueous solution.
DavidaPallin T.
Chemical Communications (Cambridge, England), 11, 1345-1346 (1996)
Reducing graphene oxide via hydroxylamine: a simple and efficient route to graphene.
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The Surface-enhanced Raman spectroscopy (SERS) method based on gold nanoparticles as SERS substrate was investigated for the label-free detection and quantification of probiotic bacteria that are widely used in various pharmaceutical formulations. Indeed, the development of a simple and fast
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Flutamide (2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide), a nonsteroidal antiandrogen, is used in the treatment of prostate cancer but is occasionally associated with hepatic dysfunction. In the present study, the metabolism of flutamide including the formation of the possible reactive toxic metabolites was investigated using
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