343773
Deuterium oxide
99.9 atom % D, contains 1 % (w/w) 3-(trimethylsilyl)-1-propanesulfonic acid, sodium salt (DSS)
Synonym(s):
Heavy water, Water-d2
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About This Item
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isotopic purity
99.9 atom % D
Quality Level
form
liquid
contains
1 % (w/w) 3-(trimethylsilyl)-1-propanesulfonic acid, sodium salt (DSS)
technique(s)
NMR: suitable
bp
101.4 °C (lit.)
mp
3.8 °C (lit.)
SMILES string
[2H]O[2H]
InChI
1S/H2O/h1H2/i/hD2
InChI key
XLYOFNOQVPJJNP-ZSJDYOACSA-N
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Application
Deuterium oxide can serve as a solvent in the :
- NMR analysis.
- 1HDOSY (Diffusion-Ordered Spectroscopy) NMR experiments.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Structure of water and hydrophobic bonding in proteins. IV. The thermodynamic properties of liquid deuterium oxide.
J. Chem. Phys. , 41(3), 680-689 (1964)
The ionization constant of deuterium oxide from 5 to 50?.
The Journal of Physical Chemistry, 70(12), 3820-3824 (1966)
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A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body
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Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated
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