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246557

Sigma-Aldrich

Tryptamine hydrochloride

99%

Synonym(s):

2-(3-Indolyl)ethylamine hydrochloride, 3-(2-Aminoethyl)indole hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H12N2 · HCl
CAS Number:
343-94-2
Molecular Weight:
196.68
Beilstein:
3568419
EC Number:
206-446-4
MDL number:
MFCD00012682
UNSPSC Code:
12352100
PubChem Substance ID:
24278134
NACRES:
NA.22

Assay

99%

form

powder

mp

253-255 °C (lit.)

solubility

water: soluble 0.1 g/10 mL, clear to slightly hazy, colorless to yellow

functional group

amine

SMILES string

Cl[H].NCCc1c[nH]c2ccccc12

InChI

1S/C10H12N2.ClH/c11-6-5-8-7-12-10-4-2-1-3-9(8)10;/h1-4,7,12H,5-6,11H2;1H

InChI key

KDFBGNBTTMPNIG-UHFFFAOYSA-N

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General description

The fluorescence property of tryptamine hydrochloride was studied in reverse micelles solution made with benzylhexadecyldimethylammonium chloride (BHDC) in benzene.

Application

Reactant for preparation of:
  • Tryptamine derivatives as inhibitors against hepatitis B virus
  • Carbamoyl epipodophyllotoxins as potential antitumor agents
  • Anthranilic acid derivatives as CCK receptor antagonists
  • Brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors
  • Antispasmodic agents
  • β-carbolinium cations as new antimalarial agents

Biochem/physiol Actions

Vasoactive; may have a neuromodulator function.

Other Notes

Biogenic amine formed from the decarboxylation of tryptophan by L-aromatic amino acid decarboxylase.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H317,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1A

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCS4947
MKCK1360
MKBZ1617V
MKBH7797V
MKBC2907V

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Jinxiu Guo et al.
Journal of chromatography. A, 1477, 132-140 (2016-12-03)
Plastic microchips have been broadly used as disposable microfluidic devices, but the poorly defined surface properties limit their application. Herein, we proved that an anionic polymer could be used as the background electrolyte (BGE) to provide a strong and stable
Davood Zare et al.
Food chemistry, 221, 936-943 (2016-12-17)
There is an increasing concern about the quality and quality assessment procedures of seafood. In the present study, a model to assess fish quality based on biogenic amine contents using fuzzy logic model (FLM) is proposed. The fish used was
C D Borsarelli et al.
Photochemistry and photobiology, 73(2), 97-104 (2001-03-29)
The fluorescence properties of 3-methylindole (MI), 3-indoleacetic acid (IAA), 3-indoleethyltrimethylammonium bromide (IETA), L-tryptophan (Trp) and tryptamine hydrochloride (TA) were studied in reverse micelles solutions made with the cationic surfactant benzylhexadecyldimethylammonium chloride (BHDC) in benzene as a function of the molar
Diego E Carballo et al.
Antibiotics (Basel, Switzerland), 8(4) (2019-11-17)
Fresh sausages are highly perishable, and the preservatives allowed in these types of meat preparations are limited. Balkan-style fresh sausages were prepared in triplicate without antimicrobials (Control), with an aqueous hops extract (30 mL/kg), with Zataria multiflora Boiss essential oil
Andrej Ščavničar et al.
Journal of AOAC International, 101(5), 1542-1547 (2018-03-25)
A new method for determination of underivatized biogenic amines in cheese based on ion exchange chromatography coupled with tandem mass spectrometric detection was proposed. The method was applied to the analysis of 10 biogenic amines (trimethylamine, putrescine, cadaverine, histamine, 2-phenylethylamine
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