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Key Documents

196479

Sigma-Aldrich

2-Phenyl-4-quinolinecarboxylic acid

99%

Synonym(s):

2-Phenylcinchoninic acid, Cinchophen

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About This Item

Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

powder

mp

214-215 °C (lit.)

solubility

alcohol: soluble 1g in 120ml(lit.)
chloroform: soluble 1g in 400ml(lit.)
diethyl ether: soluble 1g in 100ml(lit.)
water: insoluble(lit.)

SMILES string

OC(=O)c1cc(nc2ccccc12)-c3ccccc3

InChI

1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)

InChI key

YTRMTPPVNRALON-UHFFFAOYSA-N

General description

2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[DISTRIBUTION AND CONTENT OF RIBONUCLEOPROTEINS IN THE SMALL INTESTINE MUCOUS MEMBRANE IN CHRONIC EXPERIMENTAL STOMACH ULCER IN DOGS].
S A DALIMOV et al.
Meditsinskii zhurnal Uzbekistana, 39, 50-53 (1963-08-01)
[Gout].
Y OSHIMA
Naika. Internal medicine, 10, 1101-1102 (1962-12-01)
Carrageenin and cinchophen ulcer.
R B FIGUEROA et al.
Current therapeutic research, clinical and experimental, 5, 70-74 (1963-02-01)
H Jingu et al.
Neuroreport, 7(15-17), 2649-2653 (1996-11-04)
This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the
Amides and hydrazides of aroylpyrivic acids. Part 6 Synthesis and study of antiinflammatory and analgesic activity of ?-aroylpyruvoyl hydrazides of 2-methyl (phenyl)-4-quinolinecarboxylic acids.
Milyutin AV, et al.
Pharmaceutical Chemistry Journal, 32(8), 422-424 (1998)

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