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188441

Sigma-Aldrich

3,3′-Diamino-N-methyldipropylamine

96%

Synonym(s):

(7-Amino-4-methyl-4-azaheptyl)amine, 1,7-Diamino-4-aza(methyl)heptane, 1,7-Diamino-4-methyl-4-azaheptane

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About This Item

Linear Formula:
CH3N(CH2CH2CH2NH2)2
CAS Number:
105-83-9
Molecular Weight:
145.25
EC Number:
203-336-8
MDL number:
MFCD00008217
UNSPSC Code:
12352100
PubChem Substance ID:
24851162
NACRES:
NA.22

vapor pressure

6 mmHg ( 110 °C)

Assay

96%

form

liquid

refractive index

n20/D 1.4725 (lit.)

bp

110-112 °C/6 mmHg (lit.)

density

0.901 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CN(CCCN)CCCN

InChI

1S/C7H19N3/c1-10(6-2-4-8)7-3-5-9/h2-9H2,1H3

InChI key

KMBPCQSCMCEPMU-UHFFFAOYSA-N

Application

3,3′-Diamino-N-methyldipropylamine was used in the synthesis of:
  • new bischromone derivatives, potential anticancer drugs
  • polyamine derivatives containing dimeric quinolone, cinnoline and phthalimide moieties
  • 3-(2,4-dinitroanilino)-3′-amino-N-methyldipropylamine

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H302,H311,H314,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

217.4 °F - closed cup

Flash Point(C)

103 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV2198
MKCL5393
MKCG5912
MKCF4644
MKBZ5748V

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Tris[2-(methylamino)ethyl]amine 97%

Sigma-Aldrich

463531

Tris[2-(methylamino)ethyl]amine

Agata Szulawska-Mroczek et al.
Archiv der Pharmazie, 346(1), 34-43 (2012-10-31)
The synthesis of new bischromone derivatives (4a-c and 5a-c) as potential anticancer drugs is described. The difference in the reactivity between 4-oxo-4H-chromene-3-carboxylic acid 2 (or its methyl ester 3) and 4-oxo-4H-chromene-3-carbonyl chloride 1 with three different polyamines: 3,3'-diamino-N-methyldipropylamine (a), 1,4-bis(3-aminopropyl)piperazine
Carla Cruz et al.
PloS one, 6(11), e27078-e27078 (2011-12-02)
Useful probes of the intracellular environment that target a specific organelle in order to allow direct observation of the changes in these regions is of high current interest. Macrocyclic ligands have already revealed themselves as important selective hosts in some
R G Anderson et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(15), 4838-4842 (1984-08-01)
We report the synthesis of a probe that permits the visualization by electron microscopy of acidic organelles in intact cells. This probe, 3-(2,4-dinitroanilino)-3'-amino-N-methyldipropylamine (DAMP), is a basic congener of dinitrophenol that readily diffuses into intact cells. Its primary and tertiary
Marta Szumilak et al.
European journal of medicinal chemistry, 45(12), 5744-5751 (2010-10-27)
The synthesis of new polyamine derivatives containing dimeric quinoline (3a-c), cinnoline (4a-c) and phthalimide (7a-c and 8a-c) moieties is described. Three different polyamines: (1,4-bis(3-aminopropyl)piperazine (a), 4,9-dioxa-1,12-dodecanediamine (b), 3,3'-diamino-N-methyldipropylamine (c) were used as linkers. The new compounds were obtained according to
Lucas Vu et al.
Theranostics, 2(12), 1160-1173 (2013-02-06)
A focused library of twenty-one cationic poly(amino ethers) was synthesized following ring-opening polymerization of two diglycidyl ethers by different oligoamines. The polymers were screened in parallel for plasmid DNA (pDNA) delivery, and transgene expression efficacies of individual polymers were compared
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