167851

4-Bromo-1-butene

97%

• Synonym(s): 1-Bromo-3-butene, 3-Butenyl bromide, 4-Bromobut-1-ene, Allylcarbinyl bromide, But-3-en-1-yl bromide
• Linear Formula: BrCH₂CH₂CH=CH₂
• CAS Number: 5162-44-7
• Molecular Weight: 135.00
• Beilstein: 1098377
• EC Number: 225-937-4
• MDL number: MFCD00000258
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850226
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.462 (lit.)
• bp: 98-100 °C (lit.)
• density: 1.33 g/mL at 25 °C (lit.)
• functional group: alkyl halide; allyl; bromo
• storage temp.: 2-8°C
• SMILES string: BrCCC=C
• InChI: 1S/C4H7Br/c1-2-3-4-5/h2H,1,3-4H2
• InChI key: DMAYBPBPEUFIHJ-UHFFFAOYSA-N

Description

General description

Stereoselective epoxidation of 4-bromo-1-butene was carried out with three alkene-utilizing bacteria: Mycobacterium LI, Mycobacterium E3 and Nocardia IP1.

Application

• 4-Bromo-1-butene was used in the synthesis of 4-(3-butenyloxy)benzoic acid.
• It was also used in the total synthesis of largazole.
• It was used in double alkylation of lactams, followed by Grubbs ring-closing metathesis, to yield gymnodimine (biotoxin).
• It was used in preparation of dienehydrazides.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H317,H319,H334,H335
• Precautionary Statements: P210 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 33.8 °F - closed cup
• Flash Point(C): 1 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves