165212

Adipoyl chloride

98%

• Synonym(s): Adipyl chloride
• Linear Formula: ClCO(CH₂)₄COCl
• CAS Number: 111-50-2
• Molecular Weight: 183.03
• Beilstein: 507709
• EC Number: 203-876-4
• MDL number: MFCD00000759
• UNSPSC Code: 12162002
• PubChem Substance ID: 24850131
• NACRES: NA.23

Properties

• Quality Level: 200
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.471 (lit.)
• bp: 105-107 °C/2 mmHg (lit.)
• density: 1.259 g/mL at 25 °C (lit.)
• SMILES string: ClC(=O)CCCCC(Cl)=O
• InChI: 1S/C6H8Cl2O2/c7-5(9)3-1-2-4-6(8)10/h1-4H2
• InChI key: PWAXUOGZOSVGBO-UHFFFAOYSA-N

Description

General description

Adipoyl chloride belongs to the class of monomers known as acid chlorides. It is commonly used in the synthesis of Nylon 66, a type of polyamide that exhibits excellent mechanical strength, chemical resistance, and heat resistance. It is widely used in the production of fibers, textiles, carpets, and engineering plastics. It can also be utilized in the synthesis of biocompatible and biodegradable polymers, such as polyesters. These polymers find applications in drug delivery systems, tissue engineering, reverse osmosis membranes, thin films, and medical implants.

Application

Adipoyl chloride can be used as:

• A coupling agent in the synthesis of PEG-PLA-PEG triblock copolymers, enabling the formation of unique polymer structures with potential applications in drug delivery systems, tissue engineering, and controlled release systems.
• A cross-linking agent in the synthesis of biodegradable aromatic-aliphatic poly(ester-amides) from monolignol-based ester dimers. These polymers possess favorable characteristics like exceptional mechanical strength, biodegradability, and thermal stability, making them suitable for a range of applications including, controlled drug delivery systems, and environmentally-friendly packaging materials.
• Used in the preparation of biphenyl end-capped liquid crystals.

Other Notes

Material may darken in storage

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 233.6 °F - closed cup
• Flash Point(C): 112 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves