154180

4-Methoxyphenethyl alcohol

99%

• Synonym(s): 2-(4-Methoxyphenyl)ethanol
• Linear Formula: CH₃OC₆H₄CH₂CH₂OH
• CAS Number: 702-23-8
• Molecular Weight: 152.19
• Beilstein: 2043563
• EC Number: 211-866-6
• MDL number: MFCD00002900
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849412
• NACRES: NA.22

Properties

• Assay: 99%
• form: solid
• bp: 334-336 °C (lit.)
• mp: 26-28 °C (lit.)
• functional group: hydroxyl
• SMILES string: COc1ccc(CCO)cc1
• InChI: 1S/C9H12O2/c1-11-9-4-2-8(3-5-9)6-7-10/h2-5,10H,6-7H2,1H3
• InChI key: AUWDOZOUJWEPBA-UHFFFAOYSA-N

Description

General description

(R)-1-(4-methoxyphenyl)ethanol {(R)-MOPE, 4-Methoxyphenethyl alcohol, 1-(4-methoxyphenyl)ethanol } is formed during the biocatalytic anti-Prelog enantioselective reduction of 4-methoxyacetophenone (MOAP) using immobilized Trigonopsis variabilis AS2.

Application

4-Methoxyphenethyl alcohol was used as an internal standard in the fluorous biphasic catalysis reaction.

4-Methoxyphenethyl alcohol was used in the preparation of 4-(2-iodoethyl)phenol, by refluxing it with 47% hydriodic acid. It may be used in the preparation of (2R^*,4R^*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline and (2R^*,4S^*)-1-n-butyl-2-methyl-4-(2-oxopyrrolidin-1-yl)-6-methoxy-1,2,3,4- tetrahydroquinoline.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves