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115746

Sigma-Aldrich

2,2,6,6-Tetramethyl-4-piperidinol

98%

Synonym(s):

4-Hydroxy-2,2,6,6-tetramethylpiperidine

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About This Item

Empirical Formula (Hill Notation):
C9H19NO
CAS Number:
Molecular Weight:
157.25
Beilstein:
105039
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

bp

212-215 °C (lit.)

mp

129-131 °C (lit.)

functional group

hydroxyl

SMILES string

CC1(C)CC(O)CC(C)(C)N1

InChI

1S/C9H19NO/c1-8(2)5-7(11)6-9(3,4)10-8/h7,10-11H,5-6H2,1-4H3

InChI key

VDVUCLWJZJHFAV-UHFFFAOYSA-N

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Application

2,2,6,6-Tetramethyl-4-piperidinol has been used to study the green and efficient method for chemoselective deoxidization of graphene oxide via the ultraviolet irradiation.
2,2,6,6-tetramethyl-4-piperidinol has been used to study the irradiation of Camptothecin (CPT) in aerated dimethylsulfoxide (DMSO) solution that leads to formation of singlet oxygen.
Used as:
  • An additive for polymer modified hindered amine light stabilizers
  • A light stabilizer for polyamide 66 fibers containing acid blue dyes

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hirohisa Sato et al.
The Journal of toxicological sciences, 41(6), 793-799 (2016-11-18)
The present study aimed to evaluate the acute locally injurious property of our most current hydroxyl radical generation system by hydrogen peroxide (H2O2) photolysis. This system, which releases 3% H2O2 with a 405-nm laser, was developed in our laboratory for
Keisuke Nakamura et al.
PloS one, 8(3), e60053-e60053 (2013-03-26)
In the present study, the bactericidal effect of photo-irradiated proanthocyanidin was evaluated in relation to reactive oxygen species formation. Staphylococcus aureus suspended in proanthocyanidin aqueous solution was irradiated with light from a laser at 405 nm. The bactericidal effect of
Fei Zhao et al.
ACS nano, 6(4), 3027-3033 (2012-03-17)
We report a green and efficient method for chemoselective deoxidization of graphene oxide via the ultraviolet irradiation catalyzed with 2,2,6,6-tetramethyl-4-piperidinol. While the sp(2)-hybridized oxygen functional groups are removed after the reduction, the epoxy and hydroxyl groups are retained in the
Vlasta Brezová et al.
Molecular biotechnology, 37(1), 48-51 (2007-10-05)
Camptothecin (CPT) is an anticancer drug that inhibits topoisomerase I (Topo I) by forming a ternary DNA-CPT-Topo I complex. However, it has also been shown that UVA-irradiated CPT in the absence of Topo I produces significant DNA damage to cancer
Shunichi Shishido et al.
Scientific reports, 8(1), 12888-12888 (2018-08-29)
In the present study, we evaluated the prooxidative mode of action of photoirradiated (+)-catechin at 400 nm in relation to reactive oxygen species generation and its possible application to disinfection. Photoirradiation of (+)-catechin at a concentration of 1 mg/mL yielded not only

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