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V2889

Sigma-Aldrich

Valeryl Salicylate

≥98% (HPLC)

Synonym(s):

2-Valeryloxybenzoic acid, Valerylsalicylic acid, vsa

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About This Item

Empirical Formula (Hill Notation):
C12H14O4
CAS Number:
64206-54-8
Molecular Weight:
222.24
MDL number:
MFCD00041466
UNSPSC Code:
12352200
PubChem Substance ID:
24724662
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

solid

color

white

mp

86-87 °C (lit.)

solubility

DMSO: 24 mL/mL
H2O: insoluble

SMILES string

CCCCC(=O)Oc1ccccc1C(O)=O

InChI

1S/C12H14O4/c1-2-3-8-11(13)16-10-7-5-4-6-9(10)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15)

InChI key

WJHZBTMHUNVIKC-UHFFFAOYSA-N

Biochem/physiol Actions

Selective, irreversible COX-1 inhibitor. The selectivity for COX-1 vs COX-2 shows the IC50 values for ovine COX-1 vs COX-2 of 0.8 μM vs. 15 mM respectively.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Epoxyeicosatrienoic acids (EETs) are synthesized from arachidonic acid by CYP/epoxygenase and metabolized by soluble epoxide hydrolase (sEH). Roles of EETs in hypoxia-induced pulmonary hypertension (HPH) remain elusive. The present study aimed to investigate the underlying mechanisms, by which EETs potentiate
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Journal of neuroinflammation, 4, 25-25 (2007-10-12)
Neuroinflammatory responses are triggered by diverse ethiologies and can provide either beneficial or harmful results. Microglial cells are the major cell type involved in neuroinflammation, releasing several mediators, which contribute to the neuronal demise in several diseases including cerebral ischemia
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Biochemical pharmacology, 159, 11-24 (2018-11-11)
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Karina Cristina Giannotti et al.
Scientific reports, 7(1), 4098-4098 (2017-06-24)
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