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Key Documents

P3558

Sigma-Aldrich

Paraplast®

for tissue embedding

Synonym(s):

Paraffin – polyisobutylene mixture

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About This Item

CAS Number:
145686-99-3
MDL number:
MFCD00131795
UNSPSC Code:
12171500
NACRES:
NA.47

form

solid

mp

56-57 °C (lit.)
56-57 °C

application(s)

hematology
histology

storage temp.

room temp

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General description

Paraplast® is a paraffin–polyisobutylene mixture for tissue embedding and infiltration. It is a refined combination of highly purified paraffin with plastic polymers. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.

Application

Paraplast® has been used for tissue embedding and in the following applications:
  • to screen major groups of vertebrates for the presence of cardiac smooth muscle and its phylogenetic distribution in terrestrial and aquatic turtles
  • to study the relationship between membrane impedance and dendrite length of hippocampal neurons
  • to compare the regenerative properties of human stem cells of the apical papilla as an alternative to other dental stem cells

Features and Benefits

  • Minimal tissue compression.
  • Produces wrinkle-free sections.
  • Excellent ribbon continuity.

Other Notes

Double filtered paraffin wax in pellet form.

Legal Information

Paraplast is a registered trademark of Leica Biosystems

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Diana B Sequeira et al.
Clinical oral investigations, 25(9), 5317-5329 (2021-02-26)
To compare the regenerative properties of human stem cells of the apical papilla (SCAPs) embedded in a platelet-rich plasma (PRP) scaffold, when implanted in vivo using an organotypic model composed of human root segments, with or without the presence of
Positive Effects of Diphlorethohydroxycarmalol (DPHC) on the Stability of the Integument Structure in Diet-Induced Obese Female Mice
Chae-Lim Kim
Development & reproduction (2015)
Jessica N Witchley et al.
Cell host & microbe, 25(3), 432-443 (2019-03-15)
Candida albicans is a gut commensal and opportunistic pathogen. The transition between yeast and invasive hyphae is central to virulence but has unknown functions during commensal growth. In a mouse model of colonization, yeast and hyphae co-occur throughout the gastrointestinal
Cristina Barrero et al.
Planta, 229(2), 235-247 (2008-10-03)
Transfer cells have specializations that facilitate the transport of solutes across plant exchange surfaces. ZmMRP-1 is a maize (Zea mays) endosperm transfer cell-specific transcriptional activator that plays a central role in the regulatory pathways controlling transfer cell differentiation and function.
Intestinal metabolism of weaned piglets fed a typical United States
or European diet with or without supplementation
of tributyrin and lactitol
A. Piva
Journal of Animal Science (2008)
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