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ADD671C

Sigma-Aldrich

HepaRG Thawing and Plating Medium Supplement

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

Pricing and availability is not currently available.

form

liquid

shipped in

dry ice

storage temp.

−20°C

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This Item
ADD621CADD640CADD641C
shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

Biopredic′s HepaRG Thawing and Plating Medium Supplement with Antibiotics can be used with all HepaRG cell lines. See user guide for detailed protocols.

Legal Information

Use of this product is subject to one or more license agreements.

HepaRG cells are patented and their use is strictly limited; consider the cells as a single use, disposable product that must be destroyed upon conclusion of a study or experiment. Propagating, reproducing, cloning, subcloning or any other use of the cells following the conclusion of a study is prohibited. Use of the cells to produce or manufacture commercial products for general sale or for use in the manufacture of products intended for general sale is prohibited. Transfer of the cells to anyone not employed within the same organization, whether for financial benefit or not, is prohibited. If you are unwilling to accept the terms of this LIMITED USE LICENSE, do not ORDER or use them, and immediately return the cells for credit. Violators of this Limited Use License will be prosecuted to the fullest extent of the law.
HepaRG is a trademark of BioPredic International company

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Catherine C Bell et al.
    Drug metabolism and disposition: the biological fate of chemicals, 45(4), 419-429 (2017-02-01)
    Reliable and versatile hepatic in vitro systems for the prediction of drug pharmacokinetics and toxicity are essential constituents of preclinical safety assessment pipelines for new medicines. Here, we compared three emerging cell systems-hepatocytes derived from induced pluripotent stem cells, HepaRG
    Maxime Demazeau et al.
    International journal of pharmaceutics, 524(1-2), 268-278 (2017-04-04)
    In this study, we evaluated cationic liposomes prepared from diether-NH
    Lindsey M Ott et al.
    SLAS discovery : advancing life sciences R & D, 22(5), 614-625 (2017-03-28)
    Drug-induced liver injury (DILI) and drug-drug interactions (DDIs) are concerns when developing safe and efficacious compounds. We have developed an automated multiplex assay to detect hepatotoxicity (i.e., ATP depletion) and metabolism (i.e., cytochrome P450 1A [CYP1A] and cytochrome P450 3A4
    Takafumi Tomida et al.
    Journal of applied toxicology : JAT, 37(3), 382-390 (2016-08-03)
    The approach for predicting the degree of drug-induced liver injury (DILI) risk was investigated quantitatively in a modified multiparametric assay using HepaRG cells. Thirty-eight drugs were classified by DILI risk into five categories based on drug labels approved by the
    Anika Mann et al.
    Human cell, 30(4), 267-278 (2017-05-21)
    HepaRG cells are widely used as an in vitro model to assess drug-induced hepatotoxicity. However, only few studies exist so far regarding their suitability to detect the effects of drugs requiring a preceding activation via the cytochrome P450 (CYP) system.

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