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71515

Sigma-Aldrich

Sodium pyrophosphate tetrabasic decahydrate

BioUltra, ≥99.5% (T)

Synonym(s):

Pyrophosphate inorganic, Sodium diphosphate tetrabasic, Tetrasodium pyrophosphate

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About This Item

Linear Formula:
Na4P2O7 · 10H2O
CAS Number:
13472-36-1
Molecular Weight:
446.06
EC Number:
231-767-1
MDL number:
MFCD00149200
UNSPSC Code:
12161700
PubChem Substance ID:
57652314
NACRES:
NA.21

product line

BioUltra

Assay

≥99.5% (T)

form

crystals

impurities

insoluble matter, passes filter test

pH

9.5-11.0 (25 °C, 0.1 M in H2O)

solubility

H2O: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

UV absorption

λ: 260 nm Amax: 0.010
λ: 280 nm Amax: 0.010

SMILES string

O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O

InChI

1S/4Na.H4O7P2.10H2O/c;;;;1-8(2,3)7-9(4,5)6;;;;;;;;;;/h;;;;(H2,1,2,3)(H2,4,5,6);10*1H2/q4*+1;;;;;;;;;;;/p-4

InChI key

VZWGHDYJGOMEKT-UHFFFAOYSA-J

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Other Notes

In assays involving ATP-pyrophosphate exchange - tryptophanyl-tRNA synthesis; Enzyme assay in which the product pyrophosphate is measured, addition of carrier pyrophosphate insures quantitative precipitation

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tryptophanyl-tRNA synthetase from beef pancreas.
L L Kisselev et al.
Methods in enzymology, 59, 234-257 (1979-01-01)
Amidophosphoribosyltransferase (chicken liver).
J M Lewis et al.
Methods in enzymology, 51, 171-178 (1978-01-01)
Matthew Prideaux et al.
PloS one, 7(5), e36786-e36786 (2012-05-16)
Osteocytes are terminally differentiated osteoblasts which reside in a mineralized extracellular matrix (ECM). The factors that regulate this differentiation process are unknown. We have investigated whether ECM mineralization could promote osteocyte formation. To do this we have utilised MLO-A5 pre-osteocyte-like
W Charles O'Neill et al.
Kidney international, 79(5), 512-517 (2010-12-03)
Pyrophosphate, which may be deficient in advanced renal failure, is a potent inhibitor of vascular calcification. To explore its use as a potential therapeutic, we injected exogenous pyrophosphate subcutaneously or intraperitoneally in normal rats and found that their plasma pyrophosphate
Bruce L Riser et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 26(10), 3349-3357 (2011-03-15)
The high rate of cardiovascular mortality in patients with end-stage renal disease (ESRD) is a significant barrier to improved life expectancy. Unique in this population is the marked development and aggressive worsening of vascular calcification (VC). Pyrophosphate (PPi), an endogenous
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