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50020

Sigma-Aldrich

β-Glycerol phosphate disodium salt pentahydrate

≥98.0% (NT)

Synonym(s):

β-GP, β-glycerolphosphate, Disodium β-glycerol phosphate pentahydrate, glycerol-2-phosphate

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About This Item

Empirical Formula (Hill Notation):
C3H7Na2O6P · 5H2O
CAS Number:
13408-09-8
Molecular Weight:
306.11
Beilstein:
3744328
EC Number:
212-464-3
MDL number:
MFCD00149083
UNSPSC Code:
41141710
PubChem Substance ID:
57651212
NACRES:
NA.25

Assay

≥98.0% (NT)

form

solid

impurities

≤2% L-α-glycerol phosphate

loss

26-32% loss on drying

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

2-8°C

SMILES string

O.O.O.O.O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na.5H2O/c4-1-3(2-5)9-10(6,7)8;;;;;;;/h3-5H,1-2H2,(H2,6,7,8);;;5*1H2/q;2*+1;;;;;/p-2

InChI key

PEMUISUYOHQFQH-UHFFFAOYSA-L

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Application

β-Glycerolphosphate (Glycerol-2-Phosphate) is used in the development of hydrogels and scaffolds that have applications in tissue engineering and cell growth and differentiation.

Biochem/physiol Actions

Beta-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression

Other Notes

Substrate for myo-inositol-1-phosphatase from bovine brain

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yoshitomo Honda et al.
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The aim of this research was to study molecular changes in the articular cartilage and subchondral bone of the tibial plateau from mice deficient in frizzled-related protein (Frzb) compared to wild-type mice by transcriptome analysis. Gene-expression analysis of the articular
Anastassia Serguienko et al.
Biological procedures online, 20, 14-14 (2018-08-07)
In vitro studies of osteoblasts traditionally use Alizarin Red as a golden standard for the detection and quantification of mineralization, which is a marker of osteoblast differentiation. However, this method presents a number of drawbacks, including the need to fix
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Scientific reports, 7(1), 10015-10015 (2017-09-01)
In the past decade, adipose tissue has become a highly interesting source of adult stem cells for plastic surgery and regenerative medicine. The adipose source offers two options for the isolation of regenerative cells: the enzymatic digestion an expensive time-consuming
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