Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

40236

Sigma-Aldrich

N,N-Dimethyldodecylamine N-oxide solution

~30% in H2O

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C14H31NO
CAS Number:
1643-20-5
Molecular Weight:
229.40
Beilstein:
1769927
MDL number:
MFCD00002049
UNSPSC Code:
12352119
PubChem Substance ID:
57649948
NACRES:
NA.25
Pricing and availability is not currently available.

description

non-ionic

Quality Level

200

form

liquid

mol wt

229.40 g/mol

concentration

~30% in H2O

technique(s)

protein quantification: suitable

refractive index

n20/D 1.378

density

0.982 g/mL at 20 °C

SMILES string

CCCCCCCCCCCC[N+](C)([O-])C

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

N,N-Dimethyldodecylamine N-oxide (DDAO), an amphoteric surfactant, is nonionic at high pH. The surfactant headgroup of amphoteric surfactants may carry positive and negative charges as the net charge is pH sensitive.[1]

Application

N,N-Dimethyldodecylamine N-oxide solution has been used:
  • to examine the individual components of solvable for the extraction of few-layer graphene (FLG)and graphene oxide (GO) from complex organic matrices
  • as a component of wash buffer, elution buffer, and anion loading buffer for the purification of the double mutant reaction centers (DM RCs)
  • in the extraction of bilirubin and biliverdin by high-performance liquid chromatography (HPLC)

Biochem/physiol Actions

N,N-Dimethyldodecylamine N-oxide (DDAO) is preferred for protein studies. It is also frequently utilized for the extraction of membrane proteins.[1]

Features and Benefits

  • Suitable for protein quantification

Pictograms

CorrosionEnvironment
GHS05,GHS09

Signal Word

Danger

Hazard Statements

H315,H318,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM8440
BCCM8439
BCCM8441
BCCL5477
BCCM4616

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Daniel Jun et al.
STAR protocols, 3(1), 101044-101044 (2022-01-04)
The formation of defined surfaces consisting of photosynthetic reaction centers (RCs) in biohybrid solar cells is challenging. Here, we start with the production of engineered RCs for oriented binding. RCs are deposited onto gold electrodes, and 6-mercapto-1-hexanol (MCH) is used
Karl B McCann et al.
Biologicals : journal of the International Association of Biological Standardization, 37(1), 32-36 (2008-10-25)
Human serum albumin is a well tolerated therapeutic for the treatment of hypovolemia. Despite all commercial human albumin preparations being derived from plasma, these products can have a highly variable colour. Albumin samples derived from ethanol precipitation and chromatographic fractionation
David S White et al.
eLife, 9 (2020-04-09)
Single-molecule approaches provide enormous insight into the dynamics of biomolecules, but adequately sampling distributions of states and events often requires extensive sampling. Although emerging experimental techniques can generate such large datasets, existing analysis tools are not suitable to process the
Kayla D Thompson et al.
Langmuir : the ACS journal of surfaces and colloids, 38(13), 4090-4101 (2022-03-25)
Understanding the interactions between surfactants and proteins is important for the formulation of consumer products as surfactant binding can alter protein activity and stability. Additionally, the structure of the protein-surfactant complex can influence surface activity, which is important for emulsion
Thomas Kupke et al.
Communications biology, 3(1), 73-73 (2020-02-16)
Transmembrane signaling proteins play a crucial role in the transduction of information across cell membranes. One function of regulated intramembrane proteolysis (RIP) is the release of signaling factors from transmembrane proteins. To study the role of transmembrane domains (TMDs) in modulating
View All Related Papers

Protocols

Solubilization of Membrane Proteins

This page shows how to solubilize membrane proteins with products from Cytiva.

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What is the storage condition of N,N-Dimethyldodecylamine N-oxide solution? Catalog number 40236, 250mL bottle. Thanks.

    1 answer

    1. This solution may be stored at ambient temperature. It is recommended to keep the product tightly closed to preserve the integrity of the contents.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service