23131
Ethyl chloroformate
purum, ≥98.0% (GC)
Synonym(s):
Chloroformic acid ethyl ester
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About This Item
Linear Formula:
ClCOOC2H5
CAS Number:
Molecular Weight:
108.52
Beilstein:
385653
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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vapor density
3.74 (vs air)
Quality Level
vapor pressure
3.42 psi ( 20 °C)
grade
purum
Assay
≥98.0% (GC)
form
liquid
autoignition temp.
842 °F
refractive index
n20/D 1.395 (lit.)
n20/D 1.396
bp
93 °C (lit.)
mp
−81 °C (lit.)
density
1.139 g/mL at 20 °C
1.135 g/mL at 25 °C (lit.)
SMILES string
CCOC(Cl)=O
InChI
1S/C3H5ClO2/c1-2-6-3(4)5/h2H2,1H3
InChI key
RIFGWPKJUGCATF-UHFFFAOYSA-N
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Application
- GC-MS Analysis of Resveratrol Isomers in Red Wine: Application of ethyl chloroformate for derivatization of resveratrol isomers, enhancing GC-MS analysis effectiveness, crucial for quality control in food chemistry and drug discovery focusing on dietary supplements (Di Fabio et al., 2020).
- Determination of Free Aromatic Carboxylic Acids and Phenols in Juices: Uses ethyl chloroformate for rapid GC-MS analysis, important for food safety and pharmacology by verifying phenolic bioactive compounds in consumer products (Incocciati et al., 2021).
- Synthesis of Diaryl Ketones: Discusses a nickel-catalyzed method of synthesizing diaryl ketones using ethyl chloroformate, valuable for material science chemists developing new materials and pharmaceutical compounds (Shi & Hu, 2019).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
60.8 °F
Flash Point(C)
16 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A new combined gas chromatography and mass spectrometry (GC-MS) method has been developed suitable for the urine sample treatment in aqueous phase with ethyl chloroformate (ECF) derivatization agents. The method has been extensively optimized and validated over a broad range
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