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03805

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Oenothein B

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C68H48O44
CAS Number:
Molecular Weight:
1569.08
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥80% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C68H50O44/c69-22-1-14(2-23(70)39(22)79)59(93)109-56-52(92)68(112-61(95)16-5-26(73)41(81)27(74)6-16)106-34-13-103-63(97)20-11-32(46(86)50(90)38(20)37-19(64(98)107-54(34)56)9-30(77)44(84)49(37)89)104-53-21(10-31(78)45(85)51(53)91)66(100)111-58-57(110-60(94)15-3-24(71)40(80)25(72)4-15)55-33(105-67(58)101)12-102-62(96)17-7-28(75)42(82)47(87)35(17)36-18(65(99)108-55)8-29(76)43(83)48(36)88/h1-11,33-34,52,54-58,67-92,101H,12-13H2

InChI key

SHYSVHSGJVNSLX-UHFFFAOYSA-N

General description

Oenothein B is a dimeric ellagitannin compound which is found commonly in genusOenothera.

Application

Oenothein B may be used as a reference standard for the determination of oenothein B in aqueous extracts of Epilobii angustifolli herba and Epilobium angustifolium L. by high performance thin-layer chromatography (HPTLC)-densitometry, in plant materials by HPLC combined with diode array detector (DAD) and mass spectrometry (MS) and in Eucalyptus globulus leaves by HPLC-DAD coupled to electrospray ionization (EIS) MS.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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K Miyamoto et al.
Japanese journal of cancer research : Gann, 84(1), 99-103 (1993-01-01)
The antitumor effect of oenothein B, a macrocyclic ellagitannin from Oenothera erythrosepala Bordas, on rodent tumors was studied. Oenothein B exhibited a strong antitumor activity against MM2 ascites tumors upon intraperitoneal administration to the mice before or after the tumor
Barbara Hevesi Tóth et al.
Journal of pharmaceutical and biomedical analysis, 49(1), 26-31 (2008-11-18)
Epilobium species (Onagraceae) are commonly used herbal remedies in traditional, adjuvant therapy of benignus prostate hyperplasia (BPH), however the pharmacological and clinical standardization of commercially available Epilobii herba (willow-herb) remains difficult. Willow-herb products usually consist of mixtures from various species
K Aoki et al.
Biochemical and biophysical research communications, 210(2), 329-337 (1995-05-16)
Oenothein B, a macrocircular dimeric ellagitannin, was found to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B suppressed glucocorticoid-sensitive mouse mammary tumor virus (MMTV) transcription in 34I cells. This suppression was accompanied by inhibition of glucocorticoid-induced endogeneous
A Kiss et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 13(4), 284-289 (2006-02-24)
An aqueous extract of Epilobium angustifolium and its main compound oenothein B (OeB), a dimeric macrocyclic ellagitannin, are specifically able to induce the neutral endopeptidase (NEP) in prostate cancer cells. The angiotensin-converting enzyme (ACE) is not influenced. Additionally, a weak
Agnieszka Bazylko et al.
Journal of chromatography. A, 1173(1-2), 146-150 (2007-11-06)
A method was developed for separation and quantitative determination of oenothein B (OeB) and quercetin glucuronide (QG) in aqueous extract of Epilobii angustifolii herba by HPTLC-densitometry. The analyses were performed on HPTLC RP-18 WF(254) plates with 25% MeCN in water

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