ABN44
Anti-FGF10 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2
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All Photos(5)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
species reactivity (predicted by homology)
rhesus macaque (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... FGF10(2255)
General description
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor family and plays an essential role in the regulation of cell differentiation, tissue repair, tumor growth, embryonic development, and cell proliferation. Mutations in FGF10 have been associated lacrimo-auriculo-dento-digital syndrome (LADDS) which is a form of ectodermal dysplasia.
Immunogen
KLH-conjugated linear peptide corresponding to human FGF10.
Application
Detect FGF10 using this Anti-FGF10 Antibody validated for use in WB, IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western Blot Analysis: 0.5 µg/mL from a representative lot detected FGF10 on 10 µg of mouse embryo tissue lysate.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FGF10 in mouse epithelial cells, mouse liver, human brain, and human cerebellum tissues.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FGF10 in mouse epithelial cells, mouse liver, human brain, and human cerebellum tissues.
Quality
Evaluated by Western Blot in A549 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected FGF10 on 10 µg of A549 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected FGF10 on 10 µg of A549 cell lysate.
Target description
~23 kDa observed
Physical form
Affinity purified
Purified Rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4) and 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
A549 cell lysate
A549 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Nan Wang et al.
Cell proliferation, 55(11), e13315-e13315 (2022-07-20)
Ultraviolet light B (UVB) irradiation can induce skin injury and result in keratinocytes proliferation inhibition. However, the molecular understanding of the repair during UVB-induced cell proliferation inhibition remains poorly understood. The purpose of this study was to explore the role
Shawn Liang et al.
Development (Cambridge, England), 145(2) (2018-01-24)
The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ
Roberta Haddad-Tóvolli et al.
American journal of physiology. Endocrinology and metabolism, 324(2), E154-E166 (2023-01-05)
Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic diseases in the offspring. Studies have shown that it leads to hypothalamic inflammation in the progeny, affecting the function of neurons regulating food intake and energy expenditure. In
Grinu Mathew et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(46), 13156-13161 (2016-11-02)
Deficiency in PTEN (phosphatase and tensin homolog deleted on chromosome 10) is the underlying cause of PTEN hamartoma tumor syndrome and a wide variety of human cancers. In skin epidermis, we have previously identified an autocrine FGF signaling induced by
Thomas Volckaert et al.
Developmental cell, 43(1), 48-59 (2017-10-11)
The lung harbors its basal stem/progenitor cells (BSCs) in the protected environment of the cartilaginous airways. After major lung injuries, BSCs are activated and recruited to sites of injury. Here, we show that during homeostasis, BSCs in cartilaginous airways maintain
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