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ABE607

Sigma-Aldrich

Anti-APOBEC3G Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

DNA dC->dU-editing enzyme APOBEC-3G, APOBEC-related cytidine deaminase, APOBEC-related protein, ARCD, APOBEC-related protein 9, ARP-9, CEM-15, CEM15, Deoxycytidine deaminase

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

General description

DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) is a member of the cytidine and deoxycytidylate deaminase family. APOBEC3G is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3G plays an important role in cellular defense against retroviral infection. It is expressed in spleen, testes, ovary, peripheral blood leukocytes, and several tumor cell lines.

Specificity

This antibody recognizes the N-terminus of APOBEC3G.

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human APOBEC3G.

Application

Detect APOBEC-3G using this rabbit polyclonal antibody, Anti-APOBEC3G Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected APOBEC3G in human spleen tissue.

Quality

Evaluated by Western Blotting/Peptide Inhibition Assay Analysis in Caco-2 cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 5 µg/mL of this antibody detected APOBEC3G in 15 µg of Caco-2 cell lysate.

Target description

~46 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Venkata Subba Rao Atluri et al.
Scientific reports, 6, 27864-27864 (2016-06-21)
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