Q0750

Quinidine hydrochloride monohydrate

technical grade

• Synonym(s): 6′-Methoxycinchonan-9-ol hydrochloride monohydrate
• Empirical Formula (Hill Notation): C₂₀H₂₄N₂O₂ · HCl · H₂O
• CAS Number: 6151-40-2
• Molecular Weight: 378.89
• EC Number: 205-001-1
• MDL number: MFCD00198101
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654579
• NACRES: NA.22

Properties

• grade: technical grade
• Quality Level: 200
• impurities: ≤20% Dihydroquinidine (according to USP specifications., actual content given on label)
• SMILES string: O.Cl.[H][C@@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@@H](O)c3ccnc4ccc(OC)cc34
• InChI: 1S/C20H24N2O2.ClH.H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;1H2/t13-,14-,19+,20-;;/m0../s1
• InChI key: SGVZDMWHXVXUBY-KAIFKDDSSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

Application

Studied for pharmacological activity causing energy shifts from mitochondrial respiration to glycolysis

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves