Skip to Content
Merck
All Photos(1)

Documents

E43101

Sigma-Aldrich

Ethyl chlorooxoacetate

98%

Synonym(s):

mono-Ethyl oxalyl chloride, Ethyl chloroglyoxylate, Monoethyl oxalyl chloride, Oxalic acid monoethyl ester chloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClCOCOOCH2CH3
CAS Number:
4755-77-5
Molecular Weight:
136.53
Beilstein:
506725
EC Number:
225-285-0
MDL number:
MFCD00000706
UNSPSC Code:
12352101
PubChem Substance ID:
24894549
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

reaction suitability

reagent type: oxidant

refractive index

n20/D 1.416 (lit.)

bp

135 °C (lit.)

density

1.222 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)C(Cl)=O

InChI

1S/C4H5ClO3/c1-2-8-4(7)3(5)6/h2H2,1H3

InChI key

OWZFULPEVHKEKS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Ethyl chlorooxoacetate can be used for the synthesis of:
  • α-keto esters.
  • Functionalized 3-pyrolin-2-ones.
  • Substituted arylglyoxylic acids via Friedel–Crafts acylation.
  • Substituted 9,10-phenanthrenequinones.
  • Quinoxalinone derivatives.

Signal Word

Danger

Hazard Statements

H226,H314,H335

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

105.8 °F - closed cup

Flash Point(C)

41 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Methyl adipoyl chloride 97%

Sigma-Aldrich

638560

Methyl adipoyl chloride

Synthesis of arylglyoxylic acids and their collision-induced dissociation.
Wadhwa K, et al.
Synthetic Communications, 38(24), 4434-4444 (2008)
A one-pot synthesis of functionalised 3-pyrolin-2-ones by a four-component reaction between triphenylphosphine, primary amines, dimethyl acetylenedicarboxylate and ethyl chlorooxoacetate.
Anary-Abbasinejad M, et al.
J. Chem. Res. (M), 2007(10), 574-574 (2007)
A Convenient Synthesis of alpha-Keto Esters Using Ethyl 2-Pyridyl Oxalate.
Lee, Jae In
J. Korean Chem. Soc., 48(1), 103-103 (2004)
Microwave assisted synthesis of novel imidazo [2, 1-b] thiazole derivative attached to quinoxalinones.
Mukherjee C, et al.
Tetrahedron Letters, 53(45), 6008-6014 (2012)
An Efficient and Scalable Synthesis of Substituted Phenanthrenequinones by Intramolecular Friedel- Crafts Reaction of Imidazolides.
Yoshikawa N, et al.
Organic Letters, 9(21), 4103-4106 (2007)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service