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Key Documents

D124001

Sigma-Aldrich

3,5-Diiodosalicylic acid

99%

Synonym(s):

2-Hydroxy-3,5-diiodobenzoic acid, 3,5-Diiodo-2-hydroxybenzoic acid

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About This Item

Linear Formula:
I2C6H2(OH)CO2H
CAS Number:
Molecular Weight:
389.91
Beilstein:
2615358
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

powder

mp

220-230 °C (dec.) (lit.)

SMILES string

OC(=O)c1cc(I)cc(I)c1O

InChI

1S/C7H4I2O3/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2,10H,(H,11,12)

InChI key

DHZVWQPHNWDCFS-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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P B Chen et al.
Infection and immunity, 58(10), 3394-3400 (1990-10-01)
The effects of immunization in modulating the pathogenesis of Bacteroides (Porphyromonas) gingivalis infection in a murine model system were examined. BALB/c mice were immunized by intraperitoneal injection with B. gingivalis ATCC 53977 (one injection per week for 3 weeks), or
D Riendeau et al.
Molecular and cellular biochemistry, 71(1), 45-52 (1986-06-01)
Lithium diiodosalicylate (LIS) was used to selectively solubilize proteins from purified intestinal brush border membrane vesicles. Incubation of the vesicles with increasing concentrations of LIS resulted in the progressive release of proteins with total disruption of the membranes being obtained
[Zona pellucida of the mammalian egg: unique extracellular matrix].
J Dietl
Die Naturwissenschaften, 73(2), 89-94 (1986-02-01)
A J Wyrobek et al.
Molecular reproduction and development, 27(3), 200-208 (1990-11-01)
Human sperm nuclei were isolated with mixed alkyltrimethylammonium bromide and dithiothreitol (MATAB/DTT) and decondensed by treatments with lithium diiodosalicylate (LIS), sodium chloride, or Tris salts. Concentrations as low as 1 mM LIS induced measurable nuclear swelling compared to 600 mM
P Belgrader et al.
Journal of cell science, 98 ( Pt 3), 281-291 (1991-03-01)
Different agents have been employed to extract the histones and other soluble components from isolated HeLa S3 nuclei during nuclear matrix isolation. We report that 0.2M (NH4)2SO4 is a milder extracting agent than NaCl and LIS (lithium 3,5-diiodosalicylate), on the

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