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Merck
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Key Documents

1623604

USP

Succinylmonocholine chloride

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

2-(3-Carboxy-1-oxopropoxy)-N,N,N-trimethylethanaminium chloride

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About This Item

Fórmula empírica (notación de Hill):
C9H18ClNO4
Número de CAS:
5297-17-6
Peso molecular:
239.70
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

succinylcholine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C9H17NO4.ClH/c1-10(2,3)6-7-14-9(13)5-4-8(11)12;/h4-7H2,1-3H3;1H

InChI key

LDHMZIUMVSRSIK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Succinylmonocholine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Succinylcholine Chloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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I Yasuda et al.
Anesthesiology, 57(4), 289-292 (1982-10-01)
The mechanism of bradycardia caused by the administration of succinylcholine has not been fully elucidated. Accordingly, the effects of succinylcholine and succinylmonocholine on the sinoatrial node were studied in 35 mongrel dogs. The sinus node artery was selectively perfused with
Uta Kuepper et al.
Forensic science international, 207(1-3), 84-90 (2010-10-12)
Doubts concerning the applicability of succinylmonocholine (SMC) as a succinylcholine (SUX) marker have been issued. A comparative analysis of previously discussed tissues, i.e. brain, liver and kidney, was conducted to further elucidate this question by searching for diagnostically useful differences
M M Andrews et al.
The Journal of pharmacy and pharmacology, 39(3), 173-179 (1987-03-01)
The effects of equimolar concentrations (3.0 X 10(-5) M) of succinylcholine (SCh) and succinylmonocholine (SMC) were studied in-vitro at 20 degrees C in rat extensor digitorum longus muscle (EDL) 0-147 days after common peroneal nerve section. Analysis of simultaneous measurements
Succinylmonocholine identified in negative control tissues.
Marc LeBeau et al.
Journal of analytical toxicology, 27(8), 600-601 (2003-12-17)
Uta Kuepper et al.
International journal of legal medicine, 126(2), 259-269 (2011-09-29)
The muscle relaxant succinylcholine (SUX) evokes respiratory paralysis, and numerous cases of fatal SUX intoxication have been reported. Detection of SUX and its metabolite succinylmonocholine (SMC) is difficult, both due to their (bis-) quaternary structure and the extreme hydrolytic susceptibility
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