567507-U

Discovery^® HS F5 (3 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Sinónimos: Discovery Pentafluorophenyl PFP HPLC Column
• Código UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Propiedades

• Nombre del producto: Columna para HPLC Discovery^® HS F5, 3 μm particle size, L × I.D. 15 cm × 4.6 mm
• Materiales: stainless steel column
• Nivel de calidad: 100
• Agency: suitable for USP L43
• Línea del producto: Discovery^®
• Características: endcapped
• fabricante / nombre comercial: Discovery^®
• envase: 1 ea of
• Extensión del etiquetado: 12% Carbon loading
• Parámetros: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• técnicas: HPLC: suitable; LC/MS: suitable
• L × D.I.: 15 cm × 4.6 mm
• superficie: 300 m²/g
• cobertura de la superficie: 4 μmol/m²
• impurezas: <10 ppm metals
• Matriz: silica gel, high purity, spherical particle platform; fully porous particle
• grupo activo de la matriz: PFP (pentafluorophenyl) phase
• tamaño de partícula: 3 μm
• tamaño de poro: 120 Å
• Intervalo de pH operativo: 2-8
• aplicaciones: food and beverages
• técnica de separación: reversed phase

Descripción

Descripción general

Características de la Discovery^® HS F5:
• Selectividad única
• Retención similar a la C18 (algunas veces requiere una fase móvil más fuerte)
• Excelente forma del pico
• Estable, escaso sangrado en separaciones de CL/EM (LC/MS)
• Separaciones modulables de 3 a 10μm

The Discovery® HS F5 bonded phase provides reversed-phase separations that are distinctly different from C18 columns. However, compounds will generally elute within the same retention time window, making most C18 methods easily transferable.

Aplicación

• Nature of the main contaminant in the drug primaquine diphosphate: SFC and SFC-MS methods of analysis.: This study uses the Discovery^® HS F5 HPLC Column to identify and quantify the main contaminant in primaquine diphosphate, crucial for ensuring the quality and safety of this antimalarial drug (Brondz et al., 2007).
• HPLC assisted chemobiological standardization of alpha-glucosidase-I enzyme inhibitory constituents from Piper longum Linn-An Indian medicinal plant.: Demonstrates the application of the Discovery^® HS F5 HPLC Column in the biologically relevant chemical analysis of Indian medicinal plants, contributing to the standardization of herbal medicine (Pullela et al., 2006).
• Disposition study of a new potential antineoplastic agent dimefluron in rats using high-performance liquid chromatography with ultraviolet and mass spectrometric detection.: Utilizes the Discovery^® HS F5 HPLC Column to study the pharmacokinetics and metabolism of a novel anticancer agent, aiding in the development of effective cancer therapies (Císar et al., 2005).
• A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes.: This research employs the Discovery^® HS F5 HPLC Column to simplify the analysis of a phenotyping cocktail, enhancing the assessment of drug metabolism and facilitating personalized medicine approaches (Jerdi et al., 2004).

Características y beneficios

• Unique selectivity
• Similar retention to C18 (sometimes requires stronger mobile phase)
• Excellent peak shape
• Stable, low-bleed LC-MS separations
• Scalable separations from 3 to 10μm particle sizes

Productos recomendados

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Información legal

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany