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Key Documents

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SMB00083

Sigma-Aldrich

Sweroside

≥95% (LC/MS-ELSD)

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About This Item

Fórmula empírica (notación de Hill):
C16H22O9
Número de CAS:
14215-86-2
Peso molecular:
358.34
MDL number:
MFCD09954487
UNSPSC Code:
12352205
PubChem Substance ID:
329824761
NACRES:
NA.25

assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C16H22O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2,6-8,10-13,15-20H,1,3-5H2/t7-,8+,10-,11-,12+,13-,15+,16+/m1/s1

InChI key

VSJGJMKGNMDJCI-ZASXJUAOSA-N

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General description

Natural product derived from plant source.
Sweroside is an active component of iridoid glycoside, with a molecular weight of 358.344 Da. It is found in variety of plant species.

Application

Sweroside has been used as a standard in MC-high performance liquid chromatography (HPLC)-ultraviolet (UV) experiment.

Biochem/physiol Actions

Sweroside possesses hepatoprotective, antitumor, antibacterial and antifungal properties. It can be used as a potential therapeutic to treat osteoporosis.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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M M Horn et al.
Phytochemistry, 57(1), 51-56 (2001-05-05)
From the rootstock of Scabiosa columbria L. loganin and sweroside were isolated. Sweroside showed moderate antibacterial activity. Pure sweroside was converted to the sweroside aglycone 1-acetoxy derivative (DABCO/Ac2O) after hydrolysis of the glucose unit. X-ray crystallography of the monoacetate showed
Zhong-Duo L Yang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(3), 269-272 (2008-06-10)
To study the chemical constituents of the root of Hemerocallis fulva. Compounds were isolated by repeated silica gel, Sephadex LH-20, MCI gel, etc. column chromatography and their structures were determined by spectral analyses and physicochemical properties. From the n-butanol fraction
Anne T Stevens et al.
Organic & biomolecular chemistry, 7(17), 3527-3536 (2009-08-14)
A Diels-Alder cycloaddition approach to the sweroside aglycone intermediate of iridoids was explored using silylated butenolides and levoglucosenone as dienophiles under both Lewis acid and thermal conditions. Results of this study reveal no evidence that using less sterically demanding derivatives
Hui Sun et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(17), 2161-2164 (2008-12-11)
To elucidate the promoting effect of the constituents in plasma after oral administration of Liuwei Dihuangwan on proliferation of rat osteoblast. To add the constituents in plasma after oral administration of Liuwei Dihuangwan with rational concentration into culture solution of
Satyendra Suryawanshi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 858(1-2), 211-219 (2007-09-18)
Extracts from Swertia chirata (family Gentianaceae) have antidiabetics and antioxidant activity, largely attributed to the flavonoids and secoiridoids, which are a major class of functional components in methanolic extracts from aerial part of plants. In order to facilitate analysis of
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