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Merck

SMB00081

Sigma-Aldrich

Wogonoside

≥95% (LC/MS-ELSD)

Sinónimos:

5,7-Dihydroxy 8-methoxyflavone 7-glucuronide, Glychionide B, Oroxindin, Wogonin 7-glucuronide

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About This Item

Fórmula empírica (notación de Hill):
C22H20O11
Número de CAS:
Peso molecular:
460.39
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

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assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc(O)c3C(=O)C=C(Oc13)c4ccccc4

InChI

1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1

InChI key

LNOHXHDWGCMVCO-NTKSAMNMSA-N

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General description

Natural product derived from plant source.

Biochem/physiol Actions

Wogonoside, a flavanoid, is known for its anti-inflammatory properties. Wogonoside may have therapeutic potential for use in diseases which involve the development of inflammation and angiogenesis through its inhibition of LPS-induced angiogenesis.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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    Yan Yan et al.
    Chinese medicine, 13, 54-54 (2018-11-06)
    Microbial fermentation has been widely applied in traditional Chinese medicine (TCM) for thousands of years in China. Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, antioxidative activity, and neuroprotective
    Yan Chen et al.
    Toxicology, 259(1-2), 10-17 (2009-05-12)
    Wogonoside, one flavonoid derived from the root of Scutellaria baicalensis Georgi, has been reported for its anti-inflammation activity; however, whether it can inhibit inflammation-induced angiogenesis is still unclear. In the present study, we evaluated the effect of wogonoside on lipopolysaccharide
    R Xiao et al.
    Human & experimental toxicology, 36(11), 1169-1176 (2016-12-13)
    Wogonoside is the main flavonoid of the traditional Chinese medicinal herb Scutellaria baicalensis Georgi and has been found to induce growth suppression in myelogenous leukemia cells. However, its activity in T acute lymphoblastic leukemia (T-ALL) is still unclear. In this
    Xiao-Yan Wei et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1061-1062, 248-255 (2017-08-02)
    A rapid, sensitive, and selective UPLC-TQ-MS/MS method was established and validated for the determination and pharmacokinetic investigation of rhein, coptisine, berberine, palmatine, baicalin and wogonoside from Sanhuang Xiexin Decoction (SXD) extracts. A Waters BEH C
    Ying Wang et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(20-21), 1820-1826 (2009-06-06)
    A specific ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method was developed for the simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin in rat plasma. Chromatographic separation was performed on a C(18) column packed with 1.7 microm particles by a linear

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