SAB5200921

Monoclonal Anti-Notch1 - Percp antibody produced in mouse

clone S253-32, purified immunoglobulin

• Sinónimos: Anti-Motch, Anti-Neurogenic locus notch homolog protein 1, Anti-Neurogenic locus notch protein homolog, Anti-TAN1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: Peridinin-Chlorophyll-Protein Complex
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: S253-32, monoclonal
• Formulario: buffered aqueous solution
• mol peso: antigen predicted mol wt >270, ~120 kDa
• reactividad de especies: mouse, rat, human
• concentración: 1 mg/mL
• técnicas: immunocytochemistry: suitable; western blot: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NP_032740.3
• Nº de acceso UniProt: Q07008
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Notch1(18128)

Descripción

Descripción general

The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.

Inmunógeno

Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1

Acciones bioquímicas o fisiológicas

The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable