SAB4502518

Anti-KCNT1 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: KCa4.1, Potassium channel subfamily T member 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 138 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: Q5JUK3
• UniProt accession no.: Q5JUK3
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KCNT1(57582)

Descripción

General description

Anti-KCNT1 antibody detects endogenous levels of total KCNT1 protein.

The KCNT1 (potassium sodium-activated channel subfamily T member 1) gene is mapped to human chromosome 9q34.3. It is widely expressed in the brain, heart and dorsal root ganglia and well distributed in the nervous system.

Immunogen

The antiserum was produced against synthesized peptide derived from human KCNT1.

Immunogen Range: 1019-1068

Biochem/physiol Actions

Mutations in KCNT1 (potassium sodium-activated channel subfamily T member 1) is observed in different epileptic disorders including epileptic encephalopathy, nocturnal frontal lobe epilepsy and malignant migrating partial seizures in infancy. KCNT1 is associated with neural oscillation and general learning disability. It also controls pain sensation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable