SAB4501587

Anti-Integrin β3 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CD61, GP3A, GPIIIa, ITB3, integrin β-3
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 87 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P05106
• UniProt accession no.: P05106
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ITGB3(3690)

Descripción

General description

Anti-Integrin β3 Antibody detects endogenous levels of total Integrin β3 protein.

ITGB3 (integrin subunit β 3) codes for integrin αIIbβ3. It is located on human chromosome 17q21.31-32.

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin beta3.

Immunogen Range: 739-788

Biochem/physiol Actions

Mutations in ITGB3 (integrin subunit β 3) results in Glanzmann thrombasthenia (GT). It plays a major role in the movement and attack of colorectal cancer cells promoted by reactive oxygen species.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable