SAB4501062

Anti-GABA-B Receptor antibody produced in rabbit

affinity isolated antibody

• Sinónimos: G protein-coupled receptor 51, GABA-B RECEPTOR, GABABR2, GPR51, R2 SUBUNIT
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 108 kDa
• reactividad de especies: human, rat, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q9UBS5
• Nº de acceso UniProt: Q9UBS5
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GABBR1(2550)

Descripción

Descripción general

Anti-GABA-B Receptor Antibody detects endogenous levels of total GABA-B Receptor protein.

The γ-aminobutyric acid type B (GABAB) receptor is coded by the GABBR1 gene. It has 22 exons and spans at least 18 kb. GABAB gene is present between an olfactory receptor gene cluster downstream and the HLA (human leukocyte antigen) class I region upstream. It is mapped to human chromosome 6p22.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human GABA-B Receptor.

Immunogen Range: 871-920

Acciones bioquímicas o fisiológicas

The γ-aminobutyric acid type B (GABAB) is essential for the initiation by agonists like GABA (gamma-aminobutyric acid ). GABAB receptors participates in response habituation. In the visual cortex, GABAB is also involved in the initiation of orientation tuning in conjunction with GABAA receptors.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable